M. Gregory (Greg) Forest

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Primary Position: Professor of Mathematics & Applied Physical Sciences & Biomedical Engineering
Other Positions: Director of Carolina Center for Interdisciplinary Applied Mathematics
 
  • Professor, University of North Carolina at Chapel Hill, 1996-present
  • Professor, Ohio State University, 1979-1996
  • Ph.D., Mathematics, University of Arizona, August 1979
  • M.S., Mathematics, University of New Orleans, December 1973
  • B.S., Mathematics, University of New Orleans, May 1972
   
Forest Comprehensive CV September 30 2020 Published papers since 2019:
  1. Rheological Tuning of Entangled Polymer Networks by Transient Crosslinks, X. Cao, M.G. Forest, Journal of Physical Chemistry B, Vol 123(5), 974-982 (2019) https://doi.org/10.1021/acs.jpcb.8b09357
  2. Partial demixing of RNA-protein complexes leads to intra-droplet patterning in phase-separated biological condensates, K. Gasior, J. Zhao, G. McLaughlin, M.G. Forest, A. Gladfelter, J.M. Newby, Physical Review E, Vol. 99, No. 1 (2019) DOI: 10.1103/PhysRevE.99.01241
  3. Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis, C. Esther, M. Muhlebach, C. Ehre, D.B. Hill, M. Wolfgang, M. Kesimer, K. Ramsey, M. Markovetz, I. Garbarine, M.G. Forest, I. Seim, B. Zorn, C. Morrison, M. Delion, L. Turkovic, S. Ranganathan, S Stick, S. Conlan, R. Boucher, Science Translational Medicine, Vol. 11, Issue 486 (2019) DOI: 10.1126/scitranslmed.aav3488
  4. Antibody-mediated immobilization of virions in mucus, M. Jensen, Y-Y Wang, S. Lai, M.G. Forest, and S. McKinley, Bulletin of Mathematical Biology 81, 4069–4099 (2019) https://doi.org/10.1007/s11538-019-00653-6
  5. Limited processivity of single motors improves overall transport flux of self-assembled motor-cargo complexes, K. Patel, S. Mao, M.G. Forest, S. Lai, J. Newby, Physical Review E, 100, 022408 (2019) DOI: 10.1103/PhysRevE.100.022408
  6. Modeling barrier properties of intestinal mucus reinforced with IgG and secretory IgA against motile bacteria, Xu, J. Newby, T. Wessler, A. Chen, J. Schiller, H. Schroder, M.G. Forest, S. Lai, ACS Infectious Diseases 5(9), 1570-1580 (2019) https://doi.org/10.1021/acsinfecdis.9b00109
  7. Transient crosslinking kinetics optimize gene cluster interactions, B. Walker, D. Taylor, J. Lawrimore, C. Hult, D. Adalsteinsson, K. Bloom, M.G. Forest, PLoS Comp Biol 15(8): e1007124 https://doi.org/10.1371/journal.pcbi.1007124 (2019)
  8. Nanoparticle loading of unentangled polymers induces entanglement-like relaxation modes and a broad sol-gel transition, X. Cao, H. Merlitz, M.G. Forest, Physical Chem. Letters 10(17), 4968-4973 (2020) https://doi.org/10.1021/acs.jpclett.9b01954
  9. Overcoming anti-PEG, antibody-mediated, accelerated blood clearance of PEGylated liposomes by pre-infusion with high molecular weight free PEG, M. McSweeney. L. Price, T. Wessler, E. Ciociola, L. Herity, J. Piscitelli, A. DeWalle, T. Harris, A. Chan, R. Saw, P. Hu, J. Jennette, M. G. Forest, Y. Cao, S. Montgomery, W. Zamboni, S. Lai, Journal of Controlled Release, 311-312, 138-146 (2019) https://doi.org/10.1016/j.jconrel.2019.08.017
  10. Three-Dimensional Thermodynamic Simulation of Condensin as a DNA-Based Translocase, J. Lawrimore, Y. He, M.G. Forest, K. Bloom, SMC Complexes, Springer Methods in Molecular Biology, 2004, 291-318 Badrinarayanan A. (editor) (2019) https://doi.org/10.1007/978-1-4939-9520-2_21
  11. Observation of transition cascades in sheared liquid crystalline polymers, R. Fox, M.G. Forest, S. Picken, T. Dingemans, Soft Matter, 16, 3891-3901 (2020) https://doi.org/10.1039/D0SM00275E
  12. Spatial heterogeneity of the cytosol revealed by machine-learning-based 3D particle tracking, G. McLaughlin, E. Langdon, J. Crutchley, L. Holt, M.G. Forest, J. Newby, A. Gladfelter, Molecular Biology of the Cell, 31(14) (2020) https://doi.org/10.1091/mbc.E20-03-0210
  13. Fingerprinting the Nonlinear Rheology of a Liquid Crystalline Polyelectrolyte, R. Fox, M.G. Forest, C. Do, W-R Chen, S. Picken, T. Dingemans, Rheologica Acta, 59(10), 727-743 (2020) https://doi.org/10.1007/s00397-020-01234-4
  14. LPS-binding IgG arrests actively motile Salmonella Typhimurium in gastrointestinal mucus, H. Schroeder, J. Newby, A. Schaefer, B. Subramani, A. Tubbs, M.G. Forest, E. Miao, and S. Lai. Mucosal Immunology, 13(5), 814-823 (2020)
  15. Statistical mechanics of chromosomes: In vivo and in silico approaches reveal high-level organization and structure arise exclusively through mechanical feedback between loop extruders and substrate properties, Y. He, J. Lawrimore, D. Cook, E. Van Gorder, S. De Larimat, D. Adalsteinsson, M.G. Forest, K. Bloom, Nucleic Acids Research, accepted, to appear
 
  • Active microrheology of soft biological matter
  • Passive microrheology of soft biological matter
  • Nematic polymers, liquid crystals, nano-rod dispersions:  their hydrodynamics and defect morphology
  • Cell mechanics including how cells exploit liquid-liquid phase separation to sequester molecular species
  • Network graph methods and statistical transport properties of nano-rod dispersions
  • Antibody-Virus-Mucus interactions, applications to COVID-19
  • Structure and rheology of pulmonary mucus from mucin-polymer chemistry and transient charge interactions
  • Chromosome biology:  how structural maintenance of chromosome proteins act on top of the genome to guide dynamic organization
 
Address Department of Mathematics University of North Carolina Chapel Hill, NC, 27599-3250 Email forest (at) unc.edu
Telephone 919- Fax 919-962-9606
Office Phillips 316A Web site gregforest.web.unc.edu